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Drug is the first and only approved monotherapy for refractory major depressive disorder
Benefits seen for material organization, working memory, and inhibition
This trend may be driven by increases in heroin and synthetic opioids coinvolvement
47 recommendations developed in areas relevant to primary care, including transition to community, motor therapy, mental health
Antimicrobials, vaccines, anti-inflammatories linked to reduced risk for Alzheimer disease and dementia; antipsychotics and diabetes drugs tied to higher risk
From 2013 to 2023, decrease seen in healthy dietary, physical activity, and sleep behaviors, including getting enough sleep
Significantly increased risk for tardive dyskinesia seen with doses >75 mg/day at last prescription and as maximum dose
Approval marks first time the agency has approved sale of a nicotine pouch