Findings among World Trade Center responders and incidence of dementia at <65 years of age

Risk even higher with psychiatric comorbidity, particularly when diagnosed at young age

Steeper change in depressive symptoms linked to accelerated memory change and vice versa

Greater improvements reported in gratitude, anxiety, physical function at nine weeks; more improvements seen at 18 weeks

Unique environmental effects, but not a shared environment between siblings, also influences risk

Prolonged exposure beginning in young adulthood linked to worse cognitive function over midlife, especially among Blacks

Prevalence of obesity showed 1.5-fold increase in 2012 to 2023 versus 2000 to 2011