Rates of alcohol-induced deaths in 2020 increased with age, peaking for those aged 55 to 64 years

Initiating systemic hormone therapy before age 50 years linked to increased risk for depression

Rate even higher among younger adults aged 20 to 49 years, with an estimated one in five deaths

Depression scores reduced significantly for single 25-mg dose versus 1-mg dose, but not for single 10-mg dose

Chronic pain at age 44 years linked to poor mental health outcomes, pessimism about future, joblessness at age 55 years