Largest increases seen among non-Hispanic Black males aged 10 to 44 years and in American Indian, Alaska Native males aged 25 to 44 years

Improvements seen in physical and mental health, but survivors still have more symptoms than controls at two years

President Biden has ordered U.S. flags to be flown at half-staff in honor of those lost

States with greater increases in symptoms had fewer deaths from COVID-19 and lower women's unemployment rates

Yet, study shows buprenorphine is effective in protecting against overdose in this population

Maternal use of SSRIs, SNRIs in first trimester of pregnancy not linked to increased risk for neonatal seizures or childhood epilepsy in offspring

However, growth in overdose deaths has slowed compared with the 30 percent increase seen in 2020