Warnings for youth resulted in marked increases in psychotropic drug poisonings and suicide deaths

ACEs contribute substantially to suicide attempts, seriously considering attempting suicide, prescription opioid misuse

Frequent use linked to higher prevalence of bullying victimization, persistent feelings of sadness or hopelessness

Low rates of treatment observed, with only 26 percent receiving minimally adequate mental health treatment

Highest rates seen during COVID-19 pandemic versus before pandemic and in females, those aged 14 to 17 and 18 to 22 years

Progress reversed due to increase in mortality from external causes, stagnation for cardiovascular diseases

Higher annual health care expenditures and lower quality of life reported for individuals with rheumatoid arthritis

Findings seen for doses >16 mg and emergency department or inpatient utilization

Small, but significant effects seen at six months and sustained at 12 months

Additionally, a higher prevalence of lifetime suicide plan and attempts was observed