Age-dependent U-shaped trajectories seen for depression and anxiety; symptom levels were significantly higher for survivors

Strong outcomes seen in terms of weight loss, with lower doses of semaglutide used

Reduction in interest was more pronounced among smokers

REM inhibition via receipt of antidepressant medications associated with trend toward survival benefit

However, when accounting for demographic and family-level factors, between-person differences were not significant

Fewer report using a screening tool at every well visit

In the highest-risk groups, roughly one in 12 people developed depression over the next 10 years