However, nonmedical use decreased over time

Updated opioid safety labeling is based on new data from two large postmarketing observational studies

Gestational carriers have elevated incidence rate ratio compared with those carriers who conceived unassisted or by IVF

Trends strongest for firearm homicides, White populations, and rural areas

Later-in-life challenges include increased occurrence of mental health disorders, cardiometabolic issues

Psychedelics and cannabis may offer treatment hope for eating disorder symptoms

Opioids are most often the drug class implicated in causing death

Increase in theta-beta ratio seen after treatment, correlating with improved cognitive inhibition

Worse mental health seen with both e-cigarette and/or combustible tobacco product use

Significantly greater benefit on global cognition seen for structured versus self-guided intervention over two years