Most associations, including thinner prefrontal cortex and greater whole brain volume, precede substance use initiation

Other barriers include lack of knowledge, skill, and cognitive capacity

Students less likely to use 988 Lifeline for substance use concerns compared with other mental health concerns

Reduced use associated with decreases in craving for primary drug, drug-seeking behaviors, depression severity

Higher doses of prescription psychostimulants, treatment duration positively linked to longer retention

Rapid induction to extended-release buprenorphine 300-mg injection feasible and well tolerated for those using fentanyl