Pronounced increases seen in states that introduced online sportsbooks

Risk for death higher for individuals with hospital-based care for alcohol, stimulant, opioids versus cannabis use disorder

Most associations, including thinner prefrontal cortex and greater whole brain volume, precede substance use initiation

Other barriers include lack of knowledge, skill, and cognitive capacity

Students less likely to use 988 Lifeline for substance use concerns compared with other mental health concerns

Reduced use associated with decreases in craving for primary drug, drug-seeking behaviors, depression severity