Older adults with ADRD and polypharmacy experience more symptoms, have negative health outcomes

Age, sex, irregular heart rhythm, and daily activity levels can predict cognitive decline and caregiver load over two years

Diagnostic accuracy 73 percent for dementia specialists compared with 91 percent using the APS2

Increase in plasma p-tau181 levels seen in patients with incident psychosis over follow-up versus those with psychosis at baseline

Significant associations seen between self- and study partner-reported Cognitive Function Index and tau driven by elevated Aβ

Models that enable primary care practitioners to diagnose and evaluate patients for treatment eligibility would have biggest impact on wait times

Significant benefits seen for sleep efficacy, depression, and agitation

Active tCDS improves cognitive functions in memory domain, including word recall, recall of test instructions, word recognition