Trial was the first to test a drug meant to delay or halt mental decline in people who have a genetic predisposition

Medicare spending higher for adults with a formal clinical diagnosis of dementia versus a positive screening for cognitive impairment

Highest prevalence seen for high blood pressure and not meeting aerobic physical activity guidelines, followed by obesity

Larger volume associated with severity of cognitive impairment across Alzheimer disease spectrum

Risk factors differ based on sex and race and ethnicity

Individualized multidomain interventions equally effective for improving cognition in women, men

Presence of Alzheimer disease pathology related to Stages of Objective Memory Impairment in cognitively unimpaired older adults

Less than one-quarter of older adults report they would want to take it

Associations consistent across different psychiatric conditions, for Alzheimer disease and all other dementias

Announcement comes shortly after Aduhelm maker Biogen cut the price of the drug by about half, from $56,000 to $28,000 a year