Increase of 0.13 standard deviations seen in overall liability to mental illness assuming published lead-psychopathology links are causal

Associations appear to be stronger for White teens versus Black or Asian teens

Warnings for youth resulted in marked increases in psychotropic drug poisonings and suicide deaths

Highest rates seen during COVID-19 pandemic versus before pandemic and in females, those aged 14 to 17 and 18 to 22 years

No increased rates of positive M-CHAT-R screening seen for offspring

Although uncommon, contraindicated drug pairs have been prescribed

Minor improvements seen in externalizing problems, anxiety, and attention-deficit/hyperactivity disorder

Findings highlight importance of addressing neurodevelopmental and mental health conditions in this population

Significant increases seen in all subgroups, with greatest increases for girls, American Indian or Alaska Native, and Asian or Pacific Islander preteens