Finding seen among children aged 6 to 9 years at baseline with eight-year follow-up

End of primary school may be the age of greatest vulnerability for mental health conditions

Expenditures significantly higher when medical complexity and autism overlap versus either one alone

Most associations, including thinner prefrontal cortex and greater whole brain volume, precede substance use initiation

Increase of 0.13 standard deviations seen in overall liability to mental illness assuming published lead-psychopathology links are causal

Associations appear to be stronger for White teens versus Black or Asian teens

Warnings for youth resulted in marked increases in psychotropic drug poisonings and suicide deaths

Highest rates seen during COVID-19 pandemic versus before pandemic and in females, those aged 14 to 17 and 18 to 22 years

No increased rates of positive M-CHAT-R screening seen for offspring

Although uncommon, contraindicated drug pairs have been prescribed