Approval marks first time the agency has approved sale of a nicotine pouch
Proposal suggests lowering nicotine levels in cigarettes and other tobacco products to minimally or nonaddictive levels
Most dual users either continue dual use or transition to exclusive conventional cigarette use
Those who switch to dual use or who maintain, increase smoking intensity have reduced rate of symptom resolution
Higher levels of smoking also tied to pain-related work limitations and worse self-reported health, mental health
Lower risk for medical encounters for tobacco use disorder diagnosis seen in association with semaglutide versus other antidiabetes meds
Vaping tied to greater cigarette quitting in more recent years
However, ongoing use of e-cigarettes with nicotine was high