Fifteen candidate genes account for only 0.40 percent of variation in opioid use disorder risk
Genetic diagnoses result in direct changes in management for patients with a pathogenic or likely pathogenic variant
AA genotype linked to reduced severity, but not occurrence, of TD; no association seen for rs210133 with TD occurrence, severity
Unique environmental effects, but not a shared environment between siblings, also influences risk
Difference in heritability estimated at 11.3 percent, with higher heritability for males than females
Thinner retinal layers phenotypically associated with ocular, neuropsychiatric, cardiometabolic, pulmonary conditions
Findings seen in both a genetic association study and among biobank participants
No association seen for polygenic score for depression with overall sleep duration, short sleep, or long sleep
Children with polygenic risk score for insomnia have more insomnia-related sleep problems between ages 1.5 and 15 years
Nineteen independent SNPs identified that were genome-wide significant for general addiction risk factor