Risk for AD increased for parents of individuals with ADHD; associations attenuated with decreasing genetic relatedness
Polygenic risk scores did not improve performance of predictive models relative to clinical features obtained from standard psychiatric interview
CoRSIV-based model, with a positive predictive value of 80 percent, surpassed the performance of a model based on polygenic risk score
Polygenic risk scores for bipolar disorder and schizophrenia linked to structure and function of the ventromedial prefrontal cortex