Two systematic reviews show inadequate evidence for use of treatment to suppress or lessen effect of puberty, hormone treatment

Increases in glucocorticoids in response to the Trier Social Stress Test were common for women using hormonal contraceptives

Subjective improvements seen in fatigue and mood, although no change seen in facial expression recognition task at week 6

Findings seen for transgender and gender-diverse individuals desiring testosterone therapy

Authors say findings show need for body image screening in clinical practice

Risk for self-harm reduced after initiation of melatonin, especially among adolescents with depression/anxiety

Findings for girls aged 10 to 22 with anorexia nervosa versus healthy controls

Improvement seen in appearance congruence and psychosocial functioning in transgender and nonbinary youth in the two years following initiation

In a recent study, 98 percent continued with hormone treatment at follow-up

Access to GAH during adolescence, adulthood linked to lower odds of past-year suicidal ideation versus desiring but not accessing GAH