Risk factors for menstrual irregularities include posttraumatic stress symptoms, comorbid chronic disease, smoking
Psychiatric comorbidities and familial confounding only partially explain this bidirectional association
Physical premenstrual symptoms more frequent with increasing age
Survey of patients reporting prospective diagnosis of PMDD shows high rates of self-injurious thoughts and behaviors
Women with high BMI throughout teens report significantly greater premenstrual symptoms in adulthood