1999 to 2019 saw increase in mortality rates for opioid-only and opioids in combination with other substances

A shift in the age distribution of opioid-related mortality has occurred with the highest rates now observed in younger individuals

Association stronger in most recent decades and among those with schizophrenia

Of homicides occurring at home, sevenfold increased risk for being fatally shot by spouse, partner seen for cohabitants of gun owners

But evidence suggests that reverse causation may play a role in the links between serum folate deficiency and dementia, all-cause mortality

During the pandemic, mortality in the 30 days after hospital admission for non-SARS-CoV-2 causes increased for Medicare beneficiaries

Clinical outcomes and cost-effectiveness of simulated treatment strategies for injection drug use-linked IE compared in modeling study

Proportion of overdose deaths involving these drugs increased more than threefold between 2000 and 2018

Majority of premature firearm deaths seen in men, particularly suicides in older White men and homicides in younger Black men

Risk for deaths from natural causes, unnatural causes significantly increased for persons with autism spectrum disorder