Association partially mediated by neighborhood-level socioeconomic factors
Increased risk found for mortality from infections and suicide, while risk for mortality from cancer is reduced
Years of life lost due to opioid toxicity plateaued between 2017 and 2019, then increased through 2021
Suicide rate tripled for those aged 10 to 14 years from 2007 to 2018, while homicide rates doubled from 2016 to 2021
Findings seen across drug types and most ages, even when accounting for rates of drug misuse
Fifty-six countries from six continents surpassed U.S. life expectancy during 1933 to 2021
Premature adult mortality before age 70 years seen in study of middle-aged women followed for 18 years
Decrease also seen in estimated age-adjusted COVID-19 death rate, from 115.6 to 63.1 per 100,000 persons
However, fewer than one in 20 individuals receive buprenorphine
Themes include searching for answers and processing cause of death, incidental implications of SCD event