Suicide rate was higher for males, among adults aged 45 to 54 years, and for AI/AN and non-Hispanic Whites

President Biden has ordered U.S. flags to be flown at half-staff in honor of those lost

However, growth in overdose deaths has slowed compared with the 30 percent increase seen in 2020

Greatest increases seen among younger persons aged 25 to 44 years

1999 to 2019 saw increase in mortality rates for opioid-only and opioids in combination with other substances

A shift in the age distribution of opioid-related mortality has occurred with the highest rates now observed in younger individuals

Association stronger in most recent decades and among those with schizophrenia

Of homicides occurring at home, sevenfold increased risk for being fatally shot by spouse, partner seen for cohabitants of gun owners

But evidence suggests that reverse causation may play a role in the links between serum folate deficiency and dementia, all-cause mortality

During the pandemic, mortality in the 30 days after hospital admission for non-SARS-CoV-2 causes increased for Medicare beneficiaries