Two-thirds of adults who smoked wanted to quit, about half made a quit attempt, but only 8.8 percent quit in 2022

Incentivizing smoking cessation increases cessation through 12 weeks, but not at 26 weeks, when missing data are treated as smoking

Engagement with mobile chat-based intervention associated with higher abstinence rates at three and six months

Specifically, vaping products, varenicline, and heated tobacco products tied to significantly greater odds of successful cessation

Significantly more patients receiving cytisinicline versus placebo had continuous e-cigarette abstinence at the end of treatment

Benefit seen with additional six weeks of treatment after six weeks of initial failure with varenicline or nicotine replacement

Vaping tied to greater cigarette quitting in more recent years

However, ongoing use of e-cigarettes with nicotine was high

Quit rate higher for ECs than nicotine replacement therapy; at six months, 62.8 percent in EC arm still using ECs