Does not improve primary outcome, but did improve performance on certain cognitive tasks in those with epileptiform activity
Overall, 92.2, 91.0, and 85.5 percent of Medicare beneficiaries with ADRDs, Alzheimer disease, and MCI met at least one of the exclusion criteria
0.5-mg and 1-mg tablets may contain levels of N-nitroso-varenicline at or above levels approved by the FDA
Patients with acne prescribed isotretinoin less likely to engage in suicidal behavior than those treated with antibiotics only or those in the general population
Benzodiazepine deaths increased from April-June 2019 to April-June 2020, with larger increase for illicit benzodiazepine deaths
Findings based on a systematic literature review of studies reporting the use of ketamine, esketamine for treatment-resistant depression
Rates of overdose, mental health crises increased after dose tapering among patients prescribed stable, long-term, higher-dose opioid therapy
No increased risk seen for ADHD, ASD, small for gestational age with prenatal antipsychotics exposure
Current evidence does not support increased suicidality for certain newer antiseizure medications; class warning may not be merited
High-dose buprenorphine protocol well tolerated in patients with untreated opioid use disorder; no reports of respiratory depression or sedation