Phase 1 trial will include 16 patients ages 60 to 85 years who have early, symptomatic Alzheimer disease but are otherwise in good health
Combining varenicline with nicotine patch, extending treatment from 12 to 24 weeks did not increase smoking cessation rates
However, most common product type and intent of use associated with these visits vary by age
Does not improve primary outcome, but did improve performance on certain cognitive tasks in those with epileptiform activity
Overall, 92.2, 91.0, and 85.5 percent of Medicare beneficiaries with ADRDs, Alzheimer disease, and MCI met at least one of the exclusion criteria
0.5-mg and 1-mg tablets may contain levels of N-nitroso-varenicline at or above levels approved by the FDA
Patients with acne prescribed isotretinoin less likely to engage in suicidal behavior than those treated with antibiotics only or those in the general population
Benzodiazepine deaths increased from April-June 2019 to April-June 2020, with larger increase for illicit benzodiazepine deaths
Findings based on a systematic literature review of studies reporting the use of ketamine, esketamine for treatment-resistant depression
Rates of overdose, mental health crises increased after dose tapering among patients prescribed stable, long-term, higher-dose opioid therapy