Elevated midlife cortisol linked to increased amyloid deposition in the brain

Despite increased relative recurrence risk in siblings, overall likelihood of postpartum psychosis remains low

Age-dependent U-shaped trajectories seen for depression and anxiety; symptom levels were significantly higher for survivors

In the highest-risk groups, roughly one in 12 people developed depression over the next 10 years

GLP-1 receptor agonists are associated with improvements in restrained eating, emotional eating behavior, QOL

Findings show changes in specific regions of the brain

However, increased risk of self-harm is seen before initiation of treatment, during initial phase of treatment, and after discontinuation

No protective associations seen for time outdoors, but protective effects for participation in organized sports