Race appears to be an important social determinant

Nonmarried individuals with ischemic heart disease have higher prevalence of state hopelessness than married individuals

Adults with disabilities more often report that the pandemic makes it harder for them to access care, medication

Rates of overdose, mental health crises increased after dose tapering among patients prescribed stable, long-term, higher-dose opioid therapy

Risk particularly heightened in the six months following diagnosis

Nonpsychotic perceptual disturbance at age 18 years linked to increases in midlife hallucinations, delusions, and total psychotic symptoms

Much of the poor mental health during school closures tied to established risk factors

18.3 percent of respondents aged 50 to 80 years reported worse mental health; 29.0 percent made a lifestyle change to address mental health

Findings show even higher risk among those with severe mental disorders, like schizophrenia and bipolar disorders

Findings seen in double-blind, randomized, placebo-controlled discontinuation trial that was stopped early for efficacy