Almost one in four older adults with less-than-optimal well-being at baseline regained well-being over approximately three years

Insomnia linked to faster decline in global cognition scores and increased risk for cognitive impairment in older adults

Highest posterior probabilities seen with mood and anxiety disorder co-occurrence

Physical and psychological illnesses, such as fatigue, depression, anxiety, mainly associated with later breakfast

From 2014 to 2023, the firearm suicide/suicide ratio increased among women, but remained unchanged among men

Moderate level of helping, both formal volunteering and informal helping, consistently linked to robust cognitive benefits

However, older women report less sexual distress than middle-aged women

Inverse associations seen between higher adherence to three diets with annual rate of total chronic disease accumulation

Significantly greater benefit on global cognition seen for structured versus self-guided intervention over two years

Endotoxin induced increases in Profiles of Mood States depression subscale to a greater extent in those with insomnia