Rates increased from 2001 to 2018, then decreased through 2020 and increased in 2021

Emergency department visit rate higher among males than females; peaked at age 35 to 44 years in males and at 14 to 18 years in females

Significant associations seen for suicide deaths with opioid prescriptions per capita, having any, high-dose, long-term opioid prescription

Prepandemic loneliness and lower purpose in life were the strongest predictors of new-onset suicidal ideation

However, no significant decrease seen in suicidal ideation or mortality between exercise and control groups

Car crash fatalities up in these states, but opioid overdose deaths down

Findings seen in analysis of 11 million pediatric emergency visits across 18 countries, with some differences by sex and age

Regional clozapine, ECT, and lithium treatment frequency related to lower adolescent excess suicide mortality for 15- to 19-year-olds

Periods of β-blocker treatment linked to reduced risk for psychiatric hospitalization, increased risks for suicidal behavior