Overall, 988 Suicide & Crisis Lifeline operators have answered more than 2.3 million calls and nearly 600,000 texts in the past year

Three case reports from Iceland spurred the review; two of the cases involved Ozempic

Sensitivity was 82 percent and specificity 54 percent for risk of suicide within 12 months using 1-percent cutoff

Increased rates seen for suicide attempts, suicide mortality, suicide-unrelated mortality, all-cause mortality versus nontransgender individuals

Risk highest for bisexual individuals, with risk three times higher than heterosexual individuals

Lesbian/gay people more likely to report past-year suicidal thoughts; lifetime nonsuicidal self-harm increased for lesbian, gay, bisexual groups

Suicide rate tripled for those aged 10 to 14 years from 2007 to 2018, while homicide rates doubled from 2016 to 2021

The 988 line began last year after it was changed from 1-800-273-TALK

Among teens reporting firearm possession, those with depression and/or lifetime history of suicidality more likely to have bought/traded for it

Authors say this has temporal correlation with expansion of social media and firearms