On most measures in five domains of health, transgender adolescents reported differences from cisgender adolescents

Increased rates of glucocorticoid prescription or flare, escalation, death for those with clinical activity, symptoms of a common mental disorder

Extrapolation of the findings from pivotal clinical trials to the approved indication most common for disease severity

Guidance provided for counseling of pregnant women with prenatal diagnosis, care of the child from infancy through adolescence

Guidance provided for counseling of pregnant women with prenatal diagnosis, care of the child from infancy through adolescence