Preclinical studies point to the KCNQ2/3 potassium channel as a novel target for the treatment of depression and anhedonia, a reduced ability to experience pleasure. The authors conducted the first [...]
This manuscript provides an overview of our efforts to implement an integrated electronic monitoring and feedback platform to increase patient engagement, improve care delivery and outcome of treatment, and alert [...]
A previously healthy 68-year-old man rapidly developed a severe melancholic depression following influenza infection. There is an evolving understanding of the complex and possibly bidirectional relationship between depression and inflammation. [...]
Suicide risk is high in the 30 days after discharge from psychiatric hospital, but knowledge of the profiles of high-risk patients remains limited.To examine sex-specific risk profiles for suicide in [...]
Moyamoya disease (MMD) is characterized by the progressive development of stenosis in the distal carotid territory and an abnormal vascular network. It is a rare disease with a higher prevalence [...]
Loneliness is a risk factor for many clinical conditions, but there are few effective interventions deployable at scale.To determine whether a layperson-delivered, empathy-focused program of telephone calls could rapidly improve [...]
The authors sought to identify scalable evidence-based suicide prevention strategies.A search of PubMed and Google Scholar identified 20,234 articles published between September 2005 and December 2019, of which 97 were [...]
