Current evidence base insufficient to definitively link acetaminophen use in pregnancy with autism, ADHD in offspring

Affected patients should not stop taking their medication suddenly but should contact their doctor or pharmacy immediately

Worse outcomes include greater clinical impairment, emotional distress, functional difficulties, and disability

Stronger association seen for patients with both hearing loss and allergic rhinitis than for those with either one alone

Asian, Hispanic, and Black children less likely to be prescribed medication early compared with White children

Caregivers report satisfaction with quality of intervention

Treatment linked to reduced rates of first occurrence of suicidal behaviors, substance misuse, transport accidents, criminality

Insomnia severity only partially mediates the relationship between ADHD traits and lower quality of life in adults

Agency will require a Limitation of Use section in the prescribing information of all extended-release ADHD stimulants