In creating the database, the goal is to provide something that can 'improve applicability and generalizability of findings'
Later age at menopause and hormone therapy nonuse also associated with higher regional tau
Social isolation may be a modifiable risk factor for preventing Alzheimer disease-related dementias, authors say
Barriers to health care access and other socioeconomic factors may increase vulnerability in racial/ethnic minorities
Approval of Leqembi comes after controversial approval in 2021 of Aduhelm, which met with criticism over concerns about that drug's effectiveness, safety, pricing
Significant additive <em>APOE</em> ε4 interactions seen with PTSD and TBI in veterans of European ancestry
Controversy over Aduhelm stretches back to its June 2021 approval by the U.S. Food and Drug Administration
Individuals who were independently aware of the FDA decision demonstrated reduced willingness to participate
Moderately less decline seen in cognition and function at 18 months with lecanemab versus placebo
Authors say the health of family caregivers should be monitored in clinical practices