Increase driven by individuals living in jurisdictions that permitted adult-use retailers

Age-corrected standard scores for children's attention and inhibitory control lower for those exposed to cannabis

Higher odds of past-month cannabis use linked to residing in states where cannabis is legal, past-year depressive episode

Greatest rates seen in states or territories with both adult and medical use legalization

Nadir in use was reported in 1992, with partial recovery through 2008 and substantial increases thereafter

Risk increased for attention-deficit/hyperactivity disorder, autism spectrum disorder, and intellectual disability

Proportion of patient-reported qualifying conditions with substantial, conclusive evidence of therapeutic value decreased

Prevalence was lower in Western versus Southern census regions, in states with regulations, in states with legal adult-use marijuana

Proportionately lower log odds seen for heart disease, MI, stroke, composite outcome for days of use between zero and 30 a month

For people with CUD in 2004 to 2014, specialty treatment decreased in states with medical cannabis laws with dispensary provisions