Risk for death higher for individuals with hospital-based care for alcohol, stimulant, opioids versus cannabis use disorder

Schizophrenia-associated increase seen from prelegalization to legalization of nonmedical cannabis periods

Anterior insula, medial prefrontal cortex, and dorsolateral prefrontal cortex associated with history of heavy use

Findings seen for younger adults across cannabis use disorder severity levels

For individuals reporting past-year cannabis use, decreased odds of opioid misuse observed in states with medical cannabis legalization

Increase in cannabis poisoning seen with medical cannabis laws and recreational cannabis laws

CBD did not meet primary end point comparing preingestion to postingestion anxiety, but resulted in lower anxiety levels

Increase driven by individuals living in jurisdictions that permitted adult-use retailers

Age-corrected standard scores for children's attention and inhibitory control lower for those exposed to cannabis

Higher odds of past-month cannabis use linked to residing in states where cannabis is legal, past-year depressive episode