Risk increased for attention-deficit/hyperactivity disorder, autism spectrum disorder, and intellectual disability

Proportion of patient-reported qualifying conditions with substantial, conclusive evidence of therapeutic value decreased

Prevalence was lower in Western versus Southern census regions, in states with regulations, in states with legal adult-use marijuana

Proportionately lower log odds seen for heart disease, MI, stroke, composite outcome for days of use between zero and 30 a month

For people with CUD in 2004 to 2014, specialty treatment decreased in states with medical cannabis laws with dispensary provisions

Findings show threefold higher risk compared with the general population and even higher risk among young men

No association seen between cannabis use and nonmedical opioid use in those receiving pharmacotherapies for OUD

Use more likely among unmarried or unpartnered adults and those consuming alcohol

Authors call for increased monitoring of cannabis use, particularly in people with bipolar and psychotic-spectrum disorders

Meanwhile, the sale of marijuana is still illegal on a federal level