Older adults with ADRD and polypharmacy experience more symptoms, have negative health outcomes
Findings persist regardless of intensity of physical activity
The risk for mild dementia reduced by approximately 13 percent in 'weekend warriors'
Findings seen specifically for the components of purpose in life and personal growth
Associations seen for chronic and new-onset anxiety, but not for resolved anxiety, with all-cause dementia risk
Diagnostic accuracy 73 percent for dementia specialists compared with 91 percent using the APS2
However, potential class-dependent associations may exist
Findings seen in middle-aged and older adults from the general population, free from Parkinson disease
Hypothetical patients with MCI, baseline MMSE of 28, CSF Aβ1-42 of 925 pg/mL predicted to reach MMSE of 20 after 6.0 years
Findings among World Trade Center responders and incidence of dementia at <65 years of age