<p>After controlling for lifetime comorbidities and adverse socioeconomic determinants of health, infection risk increased only for cannabis use disorder</p>
<p>Populations at higher risk for methamphetamine use disorder diversifying rapidly</p>
<p>History of TBI tied to 52 percent increased odds of prescription opioid use, 65 percent increased odds of prescription opioid misuse</p>
<p>Odds increased for developing alcohol use disorders, cannabis use disorders, other drug use disorders</p>
<p>Likelihood of using substances up when youth were stressed by pandemic-related uncertainty, family experienced material hardship</p>
<p>High-dose buprenorphine protocol well tolerated in patients with untreated opioid use disorder; no reports of respiratory depression or sedation</p>
<p>Increases seen in overdose deaths from opioids, as well as cocaine and psychostimulants</p>
<p>Those with past-year methamphetamine use also more likely to have each combination of paired outcomes or all three outcomes</p>