Odds increased for developing alcohol use disorders, cannabis use disorders, other drug use disorders

Likelihood of using substances up when youth were stressed by pandemic-related uncertainty, family experienced material hardship

High-dose buprenorphine protocol well tolerated in patients with untreated opioid use disorder; no reports of respiratory depression or sedation

Increases seen in overdose deaths from opioids, as well as cocaine and psychostimulants

Those with past-year methamphetamine use also more likely to have each combination of paired outcomes or all three outcomes