Risk by age 18 years was driven by disorders within the neurodevelopmental spectrum

For people with temporal lobe epilepsy, odds of worse cognitive phenotype seen for those in more disadvantaged ADI quintiles

Standardized mortality rate increased for those receiving monotherapy, those receiving four or more meds, those without comorbidities

Rates of depressive and anxiety symptoms increased during pregnancy and postpartum for women with epilepsy

Risks for ASD, intellectual disability may be increased with prenatal exposure to topiramate, valproate, certain duotherapies

<p>Current evidence does not support increased suicidality for certain newer antiseizure medications; class warning may not be merited</p>

<p>No significant differences in language development seen at age 2 years for children born to mothers with epilepsy</p>