Declines seen across drug classes and for most states

Trends increased among most demographic groups through mid-2023, with largest increase seen for non-Hispanic American Indian, Alaska Native persons

Exposures increased 924.3 percent in those aged 0 to 12 years, with most exposures unintentional

This trend may be driven by increases in heroin and synthetic opioids coinvolvement

2023 to 2024 saw approximately sevenfold increase in overdose deaths involving carfentanil

However, from 2013 to 2023, there was a decrease in heroin concentration

Findings seen for doses >16 mg and emergency department or inpatient utilization

Plurality of seizures in West, with 77.8 percent of seizures in the West in pill form