Rapid induction to extended-release buprenorphine 300-mg injection feasible and well tolerated for those using fentanyl

Proportion of stimulant involvement in fentanyl-involved overdose deaths increased in almost every state from 2015 to 2021

The nasal spray version of naloxone will be available at select retailers for $44.99 for a box of two doses

Fentanyl is responsible for about 70,000 deaths each year in the United States

Man who sold fentanyl to a 15-year-old girl who died of an overdose last summer has been convicted of second-degree murder

Monthly percentage of illicitly manufactured fentanyl-involved deaths with xylazine detected increased from 2.9 to 10.9 percent

Increase seen in age-adjusted drug overdose death rates involving methamphetamine, cocaine; decrease reported in death rates involving oxycodone

More than 3,000 people who died of an overdose in the United States had xylazine in their system in 2021

Among the towns where this may be happening are beach resort locations, such as Playa del Carmen and Tulum

About 90 and 83.9 percent of overdose deaths involved opioids and illicitly manufactured fentanyls