However, from 2013 to 2023, there was a decrease in heroin concentration

Regardless of prognosis, panel deemed it appropriate to continue opioids, increase monitoring, and avoid opioid tapering

Increase seen in age-adjusted drug overdose death rates involving methamphetamine, cocaine; decrease reported in death rates involving oxycodone

Proportion of deaths co-involving methamphetamine and heroin or fentanyl peaked at 61.2 percent in 2021

MethHF linked to significant morbidity, including worse heart failure symptoms compared with non-methamphetamine-related heart failure

Rural U.S. residents who use both drugs more likely to have nonfatal overdose than those who use either drug alone

From 2007 to 2019, opioid-stimulant deaths among Black people increased at more than three times the rate of White people

This was the first public safety alert the DEA has issued in six years

Populations at higher risk for methamphetamine use disorder diversifying rapidly

Those with past-year methamphetamine use also more likely to have each combination of paired outcomes or all three outcomes