Highest rates in 2023 seen in West Virginia, District of Columbia; changes in rates varied by jurisdiction across drug types
Risk for death higher for individuals with hospital-based care for alcohol, stimulant, opioids versus cannabis use disorder
Early adult excess mortality higher than expected in 2019
This trend may be driven by increases in heroin and synthetic opioids coinvolvement
Results also showed age-adjusted rate of drug overdose deaths decreased from 2022 to 2023, after increasing over 20 years
2023 to 2024 saw approximately sevenfold increase in overdose deaths involving carfentanil
Increases of 2.5-fold seen for women, 2.4-fold for Asians and Pacific Islanders, 2.5-fold in the Midwest
Findings persist regardless of intensity of physical activity
Additional benefit seen for mental health and well-being
Highest rates of SCD seen for patients with schizophrenic disease; 10-year excess loss of life expected for 18-year-olds with psychiatric disorder