One-third of those say their lives were disrupted by the overdose death

Neighborhood public assistance in early childhood associated with an increased risk for death by unnatural causes through midadulthood

During the same time period, there was a decrease seen in the percentage of overdose deaths with evidence of injection

Authors say findings support efforts to improve social isolation, loneliness

Increased hazard ratios seen for all-cause mortality and mortality due to natural and unnatural causes

Diagnosis of bipolar disorder increased odds of mortality more than history of smoking or age 60 years or older

Mortality ratio increased about threefold for pregnant and postpartum women aged 35 to 44 years

Risk for death was found to be exacerbated by comorbidities

Inverse association did not differ with caregiving frequency or when stratified by age, race-ethnicity, depressive symptoms

Increased risk seen for all-cause mortality and cardiovascular disease mortality, with links consistent across subgroups