Inverse association did not differ with caregiving frequency or when stratified by age, race-ethnicity, depressive symptoms
Increased risk seen for all-cause mortality and cardiovascular disease mortality, with links consistent across subgroups
Opioid crisis hitting those without college education the hardest
2018 to 2021 saw 41.6 percent increase in firearm death rate; 82.6 percent of deaths were in children aged 15 to 19 years
Cannabis most common illicit drug, but polysubstance use also common
Rates of increase were higher among women than men, with 2018 to 2020 age-adjusted mortality rates up by 14.7 versus 12.5 percent
Age-adjusted rate of overdose deaths involving cocaine and opioids increased more quickly than cocaine alone from 2011 to 2021
83 percent of deaths due to external causes were excess, while 51 percent of deaths due to somatic causes were excess
Association partially mediated by neighborhood-level socioeconomic factors
Increased risk found for mortality from infections and suicide, while risk for mortality from cancer is reduced