Neural changes associated with eating behaviors and psychological symptoms

Authors say findings support efforts to improve social isolation, loneliness

Findings strongest for individuals with overweight or obesity

Highest prevalence and greatest rate of increase of obesity over time seen among women with bipolar disorders

Authors say changes in body weight perception could undermine efforts to tackle obesity

Genetic evidence does not support protective effects of modest alcohol consumption on obesity traits, T2D

Significant sex differences observed for most disorders, with increased risk seen for almost all disorders among women

Decreased risk seen for cardiovascular disease, kidney failure, gout, sleep disorders, and mood disorders

Weight loss pharmacotherapy recommended as adjunct to health behavior and lifestyle treatment in children 12 years and older with obesity

Differences in youth preferences and emotional reactions seen across sex, sexual orientation, race/ethnicity, and weight status