This trend may be driven by increases in heroin and synthetic opioids coinvolvement
Higher levels of smoking also tied to pain-related work limitations and worse self-reported health, mental health
Significant increase seen in prepandemic EMS encounters, followed by immediate, significant increase with pandemic interruption
Proportion of telehealth prescriptions climbed across medications
Clinicians and policymakers need a more accurate estimate of the prevalence of problematic opioid use, authors say
CYP2D6-inhibiting antidepressants linked to worse outcomes than CYP2D6-neutral antidepressants when used with CYP2D6-metabolizing opioids
