Persons receiving medication for opioid use disorder more likely to be older, White and to have public insurance

Increase seen in age-adjusted drug overdose death rates involving methamphetamine, cocaine; decrease reported in death rates involving oxycodone

Median monthly retention rate was 22.2 percent during January 2016 through April 2022

The U.S. Food and Drug Administration approved OTC Narcan nasal spray last month to be sold without a prescription

Conditioned open-label placebo had no impact on the 90-day methadone dose, but did improve sleep quality

Increases also seen for coprescribing with opioids

However, fewer than one in 20 individuals receive buprenorphine

Significant associations seen for suicide deaths with opioid prescriptions per capita, having any, high-dose, long-term opioid prescription

Rates of precipitated withdrawal are less than 1 percent

Car crash fatalities up in these states, but opioid overdose deaths down