The U.S. Food and Drug Administration approved OTC Narcan nasal spray last month to be sold without a prescription
Conditioned open-label placebo had no impact on the 90-day methadone dose, but did improve sleep quality
Increases also seen for coprescribing with opioids
However, fewer than one in 20 individuals receive buprenorphine
Significant associations seen for suicide deaths with opioid prescriptions per capita, having any, high-dose, long-term opioid prescription
Rates of precipitated withdrawal are less than 1 percent
Car crash fatalities up in these states, but opioid overdose deaths down
The spray can already be obtained without a prescription, but currently buyers must get it from a pharmacist
Furthermore, risk for fatal drug overdose lower with receipt of medications for opioid use disorder from opioid treatment programs
Highest odds of opioid overdose seen when both the individual and another household member had opioid fills in previous six months