Black men and Black women have pronounced and increasing burden of mortality compared with Whites

Highest percentage of cocaine co-involvement seen in industries that are less physically strenuous

Threefold increase seen in unintentional drug overdose death rates from 2003 to 2019, followed by 58 percent increase through 2022

Highest rates in 2023 seen in West Virginia, District of Columbia; changes in rates varied by jurisdiction across drug types

Early adult excess mortality higher than expected in 2019

Results also showed age-adjusted rate of drug overdose deaths decreased from 2022 to 2023, after increasing over 20 years

2023 to 2024 saw approximately sevenfold increase in overdose deaths involving carfentanil

Ketamine was detected in 0.4 percent of overdose deaths and listed as involved in 0.2 percent during study period