Proportion of stimulant involvement in fentanyl-involved overdose deaths increased in almost every state from 2015 to 2021

The nasal spray version of naloxone will be available at select retailers for $44.99 for a box of two doses

Significantly increased risk observed for social or behavioral health workers, registered nurses, health care support workers

Age-adjusted rate of overdose deaths involving cocaine and opioids increased more quickly than cocaine alone from 2011 to 2021

Monthly percentage of illicitly manufactured fentanyl-involved deaths with xylazine detected increased from 2.9 to 10.9 percent

Increase seen in age-adjusted rate of drug overdose deaths involving xylazine from 0.03 to 1.06 per 100,000 standard population

Findings seen across drug types and most ages, even when accounting for rates of drug misuse

Most patients with emergency department visit for nonfatal opioid overdose were men; most frequent drugs reported were fentanyl and heroin

<p>Overdose prevention centers allow people to use illegal drugs under supervision so they can potentially be revived if they overdose</p>

Increase seen in age-adjusted drug overdose death rates involving methamphetamine, cocaine; decrease reported in death rates involving oxycodone