Sharp increase in deaths in Midwestern, Southern, Western jurisdictions; stimulant also involved in about four of 10 IMF-involved deaths

Cities and states nationwide have pushed for overdose prevention sites in recent years

Figure is almost 30 percent higher than the previous year, when 78,000 overdose deaths were reported

Record-high 96,779 drug overdose deaths reported from March 2020 to March 2021

In policy recommendations, AMA calls for removal of barriers to evidence-based care

Populations at higher risk for methamphetamine use disorder diversifying rapidly

In 2019, xylazine contributed to death in 64 percent of cases and almost always also involved fentanyl

No significant change seen in overdose death rates overall from 2018 to 2019, but rate increased among non-Hispanic Blacks

Benzodiazepine deaths increased from April-June 2019 to April-June 2020, with larger increase for illicit benzodiazepine deaths

Rates of overdose, mental health crises increased after dose tapering among patients prescribed stable, long-term, higher-dose opioid therapy