Adults identifying as bisexual or 'something else' have highest prevalence of chronic pain

Improvement observed across a range of health conditions, mostly sustained over time

Increase in proportion of patients achieving ≥15 percent reduction in daily morphine equivalent dose, ≥2-point reduction in pain intensity

Co-occurrence of symptoms also very common across cancer types

Strong recommendation made against long-term opioid therapy, especially for younger age groups, those with substance use disorder

In 11 comparisons, antidepressants were efficacious, but they were inefficacious or evidence was inconclusive for 31 comparisons

Universal screening for cannabinoids recommended before surgery; elective surgery should be postponed in some cases

Text message-based platform enhances self-efficacy for managing symptoms of IC/bladder pain syndrome

Tapering cuts risk for overdose among those with opioid use disorder

Chronic pain at age 44 years linked to poor mental health outcomes, pessimism about future, joblessness at age 55 years