No improvement seen in physical or mental health-related quality of life

Rate of complete mental health lower among adults with ADHD compared with those without ADHD

Association stronger in most recent decades and among those with schizophrenia

Rate of complete mental health lower among adults with ADHD compared with those without ADHD

Association stronger in most recent decades and among those with schizophrenia

On most measures in five domains of health, transgender adolescents reported differences from cisgender adolescents

Increased rates of glucocorticoid prescription or flare, escalation, death for those with clinical activity, symptoms of a common mental disorder

Extrapolation of the findings from pivotal clinical trials to the approved indication most common for disease severity